Honey Bee Parasites, Pests, Predators and Diseases

American foulbrood (Terramycin® antibotic)
Terramycin (oxytetracycline) is the only drug approved for use as a preventive
treatment against American foulbrood. This antibiotic does not kill Bacillus larva spores. However, when it is
present in low concentrations in the food fed by workers to susceptible larvae, terramycin prevents AFB spores
from germinating to the vegetative stage and delays vegetative growth in larvae. While this treatment allows individual
larvae to survive, it has no effect on the virulent spores in the contaminated equipment. Thus, AFB often reappears
once terramycin treatment stops.
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